Webinars & Events Archives - Page 3 of 4

Title: Keeping Track of Clinical Samples in Biomarker-Rich Clinical Trials

Duration: 30 minutes

Learn how clinical operations and translational teams are creating “sponsor-centric” visibility to reconcile sample status and location on-study.

Join QuartzBio at the SCOPE 2022 Summit for the “Clinical Biomarkers Operations and Innovation” track on February 8-9.

PRESENTATION: “30 Days to an Annotated Virtual Repository — Without Changing DTAs”

Clinical and biomarker operations teams can create ongoing visibility into sample collection, processing and testing by linking biospecimen metadata, informed consent, and biomarker data across multiple LIMS and inventories.
Mike Waters will share how teams are using technology to access a single source of truth for sample inventory management.

Register for the webinar here

Title: Advancing Clinical Sample Management with a Virtual Sample Repository

Duration: 30 minutes

You’ll see how a virtual repository delivered via QuartzBio’s translational hub provides visibility into clinical sample status:

Sample visibility across studies, central labs, third party vendors, biorepositories, and disparate source systems
KPI dashboards that report sample status including collection, processing, testing, consent, expiration – while highlighting collection gaps and discrepancies.
Dynamic visualizations to quickly review expected vs actual sample status by patient, time point, and assay type

Register for the webinar here

Title: Transcending Biomarker Data Chaos: How Integrating Disparate PK, Clinical & Exploratory Data Enables Deep Translational Insights

Duration: 30 minutes

You will see how teams unlock translational intelligence:

Navigate vast exploratory data – identify trends and data points of interest
Surface insights – analyze biomarker trends in collaborative dashboards across subject IDs, time points, response status, and treatment groups
Access data rapidly – point and click navigation to underlying data files to interrogate the raw data behind the summary values
Interrogate cross assay – map to a common data dictionary to enable rapid interrogation of trends across assay modalities: within and across studies

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Title: Overcoming Clinical Sample Chaos: A Critical Step in Biomarker-Rich Trials

Duration: 45 minutes

You’ll see how a technology-enabled approach to clinical sample inventory management delivers:

Sample KPI dashboards for clinical, translational, & data management teams
Visibility into sample collection, processing, and consent status
Dynamic visualizations to quickly review expected vs actual sample status by patient, time point, and assay type

Watch the webinar on demand:

Title: Translational Intelligence: Exploring IO Signatures in Clinical Trial Genomic Data

Duration: 30 minutes

You will learn how to:

Visualize gene alterations and tumor mutational burden (TMB) using heatmaps and tables, with subject and time point granularity.
Identify genes of interest and candidate signatures using visualization and statistical methods to relate clinical response data and gene expression data to regions of genomic alteration.
Correlate genomic data with known signatures of immuno-oncology (IO) response through integrations with public data, knowledgebases and sponsor data.
Define patient subgroups to generate deeper biological/ mechanistic insights.

April 2, 2021 — Gene expression biomarkers can help predict clinical outcomes in response to treatment with pathway-targeting therapeutics, thereby helping to identify patient subgroups likely to respond.

In a collaboration with investigators at Isofol Medical AB, the QuartzBio team analyzed the correlation between expression of folate pathway genes and clinical outcomes in response to a combination therapy targeting this pathway in metastatic colorectal cancer, as part of a Phase III clinical trial.

They identified potential prognostic markers with clinical benefit, and presented the results at the 2021 American Society of Clinical Oncology Gastrointestinal Cancers Symposium (ASCO-GI).

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March 8, 2021 — At last week’s SCOPE 2021 virtual summit for clinical operations executives and their partners, an overarching theme was the increased speed of clinical operations in response to the COVID-19 pandemic.

“Speed — is this the new normal? Can we as organizations support that ramped-up speed … with the resources that we all have?” asked moderator Michael Tanen, Director, Clinical Biomarker Specimen Management, Merck & Co., at Tuesday’s panel discussion in the Clinical Biomarkers Operations & Innovations track.

QuartzBio’s SVP of Data Management and Systems Integration, Tobi Guennel, joined leaders from Bristol-Myers Squibb, Eli Lilly, AbbVie, and Covance for this live panel.

March 5, 2021 — Applying algorithms to interconnected biomarker and clinical data can yield scientific insights, not only into therapeutic mechanisms, but also into predicting long-term response to treatment.

In a collaboration with investigators at Janssen, the QuartzBio team sought to identify genetic markers correlated with protection against chronic hepatitis B early relapse in patients after withdrawal from treatment. The team identified several genes that were, for the first time, associated with protection against early onset of relapse.

View the poster

Join QuartzBio at the SCOPE 2021 virtual conference for the “Clinical Biomarkers Operations and Innovation” track on March 2.

PRESENTATION: “Centralizing PK, Clinical, and Exploratory Biospecimen Data to Streamline Trial Operations & Intelligence”

Clinical samples are frequently a logistical headache – managed too often in Excel files that are time-consuming to update, and quickly fall out of date. Modern biomarker-centric programs demand a focused strategy to provide timely visibility into sample availability and quality.

Dr. Tobi Guennel will share how clinical teams are leveraging technology to quickly and efficiently gain visibility into their clinical samples across sites, labs, and storage facilities.